A certain transmembrane protein has its amino terminus at the exterior ... ...

A certain transmembrane protein has its amino terminus at the exterior of the cell, carboxy terminus in the cytoplasm and everything in between embedded in the membrane. Which of the following statements is true?
(A) The amino terminus must be hydrophobic.
(B) ...
(C) ...
(D) ...
(E) ...

*This question is included in 11. Plasma Membrane and Transport